250 mg in 5 ml ampoule(50 mg/ml) for IM, IV injection or infusion
Dosage
Child and adult:
Induction
IV: 2 mg/kg to be injected slowly. Anaesthesia is produced within one minute and lasts 10 to 15 minutes.
IM: 8 to 10 mg/kg. Anaesthesia is produced within 5 minutes and lasts 15 to 30 minutes.
Maintenance
IV: 0.5 to 1 mg/kg depending on recovery signs (approximately every 15 minutes)
IM:5 mg/kg approximately every 20 to 30 minutes
Duration
Depending on duration of the operation
Contra-indications, adverse effects, precautions
Do not administer to patients with intraocular hypertension, pre-eclampsia.
Administer with caution to patients with arterial or intracranial hypertension, coronary insufficiency, psychiatric disorders.
May cause: hypertension, hypersalivation, hallucinations during recovery (less frequent in children or when injectedIM), apnoea following rapid IV injection.
Premedication to prevent hypersalivation and hallucinations:
atropine IV: 0.01 to 0.015 mg/kg + diazepam slow IV: 0.1 mg/kg, during induction or
atropine IM: 0.01 to 0.015 mg/kg + diazepam IM: 0.1 mg/kg, 30 minutes before induction.
Technical equipment for intubation and ventilation must be available and ready for use.
Pregnancy: no contra-indication, exceptin pre-eclampsia. For ceaserean sections,do not exceed
1 mg/kg by IV injection (risk of neonatal respiratory depression at higher doses).
Breast-feeding: no contra-indication
Remarks
Ketamine has no muscle relaxant properties.
In some countries, ketamine is on the list of narcotics: follow national regulations.
Also comes in 10 ml ampoule containing500 mg (50 mg/ml).