Prevention of gastroenteritis due to rotavirus infection in infants
Composition, forms, route of administration
Live-attenuated monovalent human rotavirus vaccine(RV1, strain RIX4414, Rotarix®)
Oral suspension, 1.5 ml in monodoseplastic tube.
DO NOT ADMINISTER BY PARENTERAL ROUTE.
Dosage and vaccination schedule
Child from 6 weeks to 24 months: 2 doses at least 4 weeks apart. It is recommended to administer the 1stdose at 6 weeks of age and the 2nd dose at 10 weeks of age, at the same time as the first 2 doses of pentavalent vaccine (diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae).
Shake the plastic tube, squeeze the entire content of the tube into the mouth.
Contra-indications, adverse effects, precautions
Do not administer in case of acute gastroenteritis, history of intussusception, severe immuno deficiency.
Do not administer in the event of allergic reactions to a previous dose of vaccine.
Vaccination should be postponed in the event of severe acute febrile illness;minor infections are not contra-indications.
May cause: diarrhoea, abdominal pain, irritability; rarely: intussusception, anaphylactic reactions.
If the patient vomits the dose of vaccine,wait a few minutes and re-administer the same dose.
Remarks
Also comes in a monovalent human vaccine (RV1, strain 116E, Rotavac®) and pentavalent human- bovine vaccine (RV5), to be administered in 3 doses 4 week apart.
Rotavirus vaccine can be administered concomitantly with oral polio vaccine (OPV).