Podophyllotoxin 0.5% Solution or Gel

Generic Name: Podophyllotoxin

Brand Names:

Availability: Available with Prescription

Drug Class: Antimitotics

Therapeutic action

  • Antiviral, antimitotic, cytolytic agent active against human papillomaviruses (HPVs)

Indications

  • External genital warts, perianal warts and vaginal warts

Forms and strengths

  • 0.5% solution or gel, with applicator tips

Dosage

  • One application to warts 2 times daily
  • For vaginal warts, allow to dry before removing the speculum.

Duration

  • 3 consecutive days per week, for a maximum of 4 weeks

Contra-indications, adverse effects, precautions

  • Do not use to treat genital warts in children.
  • Do not apply to warts > 3 cm.
  • Do not apply to cervical, urethral, anorectal or oral warts. 
  • Do not apply to healthy skin.
  • May cause local reactions: erythema,ulceration, pain in area where applied. 
  • Use a new applicator tip for each application.
  • Avoid contact with eyes. In case of eye contactflush immediately with plenty of water.
  • Pregnancy: CONTRA-INDICATED
  • Breast-feeding: CONTRA-INDICATED

Remarks

  • When treatment is contra-indicated or has failed after 4 weeks, change treatment method(cryosurgery, electro surgery, surgical removal).

Storage

– Below 25 °C