Indications
- Prevention of typhoid fever in children as of 6 months and adults up to 45 years of age:
- in endemic areas
- in mass immunisation campaigns in the event of an outbreak or humanitarian emergency context, based on risk assessment
Composition, forms, route of administration
- Typhoid (polysaccharide) conjugate vaccine
- Suspension for injection in multidose vial, for IM injection into the anterolateral part of the thigh in children < 2 years and into the deltoid muscle in children≥ 2 years.
- DO NOT ADMINISTER INTO THE GLUTEAL MUSCLE.
Dosage and vaccination schedule
Child and adult: 0.5 ml single dose
Routine vaccination
- Child at 9 months or during the 2nd year of life:one single dose at the same time as other recommended vaccines.Follow national recommendations.
Catch-up vaccination
- Child up to 15 years: one single dose. Follow national recommendations.
Contra-indications, adverse effects, precautions
- Do not administer in case of allergic reactions to any component of the vaccine.
- Vaccination should be postponed in the event of severe acute febrile illness;minor infections are not contra-indications.
- May cause: mild reaction sat the injection site (pain, redness at the injection site), fever, headache,myalgia; rarely: anaphylactic reactions.
- If administered simultaneously with other vaccines,use different syringes and injection sites.
- Pregnancy: no contra-indication
- Breast-feeding: no contra-indication
Remarks
- Typhoid conjugate vaccine does not protect against Salmonella Paratyphi or other types of non- typhi salmonella.
- Shake before use to homogenise the vaccine.
Storage
– Between 2 °C and 8 °C. Do not freeze.
Once opened, store vial between2 °C and 8 °C for 6 hours maximum.